5-(4'-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole - Names and Identifiers
| Name | 5-(4'-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole
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| Synonyms | 5-(4'-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole
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5-(4'-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole - Introduction
5-(4 '-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole is an organic compound with the chemical formula C18H11BrN4.
It has the following properties:
1. Appearance: colorless to light yellow crystal.
2. Melting Point: about 220-225 ℃.
3. Solubility: Soluble in organic solvents such as methanol, dimethyl sulfoxide and dichloromethane.
5-(4 '-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole can be used as a drug, containing tetrazolium structure, it can be used to design and synthesize compounds with biological activity. It can also be used as an intermediate in the synthesis of materials and has potential applications in the field of materials science.
5-(4 '-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole can be prepared by the following steps:
1. The Grignard reaction of 1,1 '-dibromobenzene with tetrazolamine using a copper nickel hydride catalyst gives 4'-bromo-[1,1 '-biphenyl]-4-ylamine.
2. Reaction of 4 '-bromo-[1,1'-biphenyl]-4-ylamine with nitrosoamine to yield 5-(4 '-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole.
When using and handling 5-(4 '-bromo-[1,1'-biphenyl]-4-yl)-1H-tetrazole, you need to pay attention to the following safety information:
1. This is an organic compound that needs to be used in a well-ventilated place to avoid inhaling dust or vapor.
2. Use should wear appropriate protective gloves, glasses and protective clothing.
3. Avoid contact with skin and swallowing. In case of accidental contact, flush the affected area immediately with plenty of water. In case of discomfort, seek medical attention.
4. Storage should be away from heat source and open flame, avoid contact with oxidants and other substances.
5. Before use or disposal, carefully read and follow the relevant safety guidelines and operating procedures.
Last Update：2024-04-09 19:05:55